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Premature Rupture of The MembranesPremature rupture of the membranes (PROM) is a spontaneous break or tear in the amniochorial sac before onset of regular contractions, resulting in progressive cervical dilation. PROM occurs in nearly 10% of all pregnancies over 20 weeks' gestation, and labor usually starts within 24 hours; over 80% of these infants are mature. The latent period (between membrane rupture and labor onset) is generally brief when the membranes rupture near term; when the infant is premature, this period is prolonged, which increases the risk of mortality from maternal infection (amnionitis, endometritis), fetal infection (pneumonia, septicemia), and prematurity.CausesAlthough the cause of PROM is unknown, malpresentation and contracted pelvis commonly accompany the rupture. Predisposing factors may include:
Signs and symptomsTypically, PROM causes blood-tinged amniotic fluid containing vernix particles to gush or leak from the vagina. Maternal fever, fetal tachycardia, and foul-smelling vaginal discharge indicate infection.DiagnosisIn addition to a complete medical history and physical examination, PROM may be diagnosed in several ways, including the following:
TreatmentTreatment for PROM depends on fetal age and the risk of infection. In a term pregnancy, if spontaneous labor and vaginal delivery aren't achieved within a relatively short time (usually within 24 hours after the membranes rupture), induction of labor with oxytocin is usually required; if induction fails, cesarean delivery is usually necessary. Cesarean hysterectomy is recommended with gross uterine infection. Management of a pre-term pregnancy of less than 34 weeks is controversial. However, with advances in technology, a conservative approach to PROM has now been proven effective. With a preterm pregnancy of 28 to 34 weeks, treatment includes hospitalization and observation for signs of infection (maternal leukocytosis or fever, and fetal tachycardia) while awaiting fetal maturation. If clinical status suggests infection, baseline cultures and sensitivity tests are appropriate. If these tests confirm infection, labor must be induced, followed by I.V. administration of antibiotics. A culture should also be made of gastric aspirate or a swabbing from the infant's ear because antibiotic therapy may be indicated for the new-born as well. In such deliveries, have resuscitative equipment available to treat neonatal distress. PreventionUnfortunately, there is no way to actively prevent PROM. However, this condition does have a strong link with cigarette smoking and mothers should stop smoking as soon as possible. |
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